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Bulgaria Health System Could Perform Much Better, World Bank Says

Bulgaria Health System Could Perform Much Better, World Bank Says Bulgaria’s health care system has the potential to considerably boost its performance while cutting out-of-pocket spending, the World Bank has said. A More »

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Preventing cot death with a wi-fi router

Preventing cot death with a wi-fi router Soon wi-fi could help to prevent cot death. Vital Radio is a wireless device that can monitor a baby’s heartbeat and breathing from one room More »

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Medtronic Activa Neurostimulators Approved in Europe for Full Body MRI Scans

Medtronic Activa Neurostimulators Approved in Europe for Full Body MRI Scans Medtronic won European regulatory approval for its Activa line of deep brain stimulators (DBS) to be safe for use in full More »

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Finlands first artificial heart transplant made successfully

Finlands first artificial heart transplant made successfully The first artificial heart transplantation has been made to a patient in Helsinki. The Hospital District of Helsinki and Uusimaa (HUS) reported on Tuesday that the More »

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Probiotic bacterium to be used in Estonian dairy products for at least another decade

Probiotic bacterium to be used in Estonian dairy products for at least another decade On March 27, the University of Tartu (UT) and AS Tere, one of Estonia’s largest dairy processors, signed More »

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Could story-based video games help people with autism?

Could story-based video games help people with autism? New research into nonviolent video games suggests that games promoting storytelling over action may have prosocial benefits for people with autism. Previous research has suggested More »

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Inkjet Printing of Flexible Electronics for Body-Worn Medical Devices

Inkjet Printing of Flexible Electronics for Body-Worn Medical Devices Flexible electronics have the potential to revolutionize medicine, and they’ve already shown a lot of promise though the technology is still in an early More »

stemcell-research_1532389c

Brilliant spark for personalised therapies

Brilliant spark for personalised therapies The 2015 Spark Award goes to a group of researchers led by ETH Professor Manfred Kopf, which has developed a method by which specific characteristics of immune More »

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Even doctors rely on Dr. Google

Even doctors rely on Dr. Google In Italy, it’s not just members of the public who rely on the Internet to search for information about their health. Now the vast majority of More »

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Bras that treat breast cancer

Bras that treat breast cancer A British student, Sarah Da Costa, has created the Foxleaf Bra, a bra that releases anti-cancer drugs directly into the body. The revolutionary garment contains tamoxifen in tiny More »

Neulasta-injector

Neulasta On-body Injector Makes Sure Drug Administered Following Chemo

Neulasta On-body Injector Makes Sure Drug Administered Following Chemo Neulasta (pegfilgrastim) is administered to patients the day after chemotherapy to boost the production of white blood cells that help fight infection. Now More »

Category Archives: Technology/science

Preventing cot death with a wi-fi router

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Preventing cot death with a wi-fi router

Soon wi-fi could help to prevent cot death. Vital Radio is a wireless device that can monitor a baby’s heartbeat and breathing from one room to another. Developed by a researcher at the prestigious Massachusetts Institute of Technology (MIT) in Boston, the wireless router can pick up radio waves related to breathing or heart rates.

It can even tell if the individual is moving or still. The signals are then sent to a computer and processed through a specific programme, which can detect possible abnormalities. The brilliant idea could also prove useful in the monitoring of patients in hospitals without the need for invasive machinery.

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Medtronic Activa Neurostimulators Approved in Europe for Full Body MRI Scans

Activa-PC

Medtronic Activa Neurostimulators Approved in Europe for Full Body MRI Scans

Medtronic won European regulatory approval for its Activa line of deep brain stimulators (DBS) to be safe for use in full body MRI scans, given certain conditions. Previously, the company had approval for only head scans under MRI for patients wearing their DBS devices. The new announcement allows both future as well as existing patients to receive MRI scans of any part of the body, as long as specific precautions are taken by the radiology techs.

These are the only DBS systems to receive a full-body MR-conditional approval from the European authorities, allowing patients with Parkinson’s disease, essential tremor, refractory epilepsy, and dystonia to continue receiving medical care that requires MR scans. The implants have to be appropriately programmed before undergoing a scan, keeping them working so as to allow the acquisition of sharp images unaffected by the jerky motions associated with neuromotor disease

source: http://www.medgadget.com/2015/04/medtronic-activa-neurostimulators-approved-in-europe-for-full-body-mri-scans.html

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Finlands first artificial heart transplant made successfully

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Finlands first artificial heart transplant made successfully

The first artificial heart transplantation has been made to a patient in Helsinki. The Hospital District of Helsinki and Uusimaa (HUS) reported on Tuesday that the patient is recovering at Meilahti Hospital. The surgery was conducted on April 16 and was led by cardiothoracic surgeon Karl Lemström from HUS.

“The surgery itself lasted 3-4 hours. The initial and final preparations into the operation went on throughout the day,” he said. A control unit outside the body regulates the artificial heart’s functions. The artificial heart works on compressed air the same way as the natural one does. Vacuum and pressure variation between the membrane and the chambers of the deoxygenated and oxygenated blood is moved to the right places. Constriction in the chest is regulated by passing through the compressed air hoses. Lemström said the size of the artificial heart is about that of two oranges. The space between the patient’s sternum and the spine will thus be 10 centimetres.“The treated patients must be adults. The artificial heart is not suitable for children,” he added.

Only a few artificial heart transplants have been carried out in Nordic countries. According to Lemström, about 1,500 artificial heart transplants have been carried out worldwide.

source: http://www.finlandtimes.fi/health/2015/04/22/16165/Countrys-first-artificial-heart-transplant-made-successfully

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Probiotic bacterium to be used in Estonian dairy products for at least another decade

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Probiotic bacterium to be used in Estonian dairy products for at least another decade

On March 27, the University of Tartu (UT) and AS Tere, one of Estonia’s largest dairy processors, signed a ten-year extension to the exclusive licence agreement that allows Tere to continue using the Lactobacillus fermentum ME-3 bacterium discovered by the UT researchers in the production and marketing of dairy products in Estonia and twelve other European countries.

According to Erik Puura, UT’s vice rector for development, the stable and substantive partnership of the university and the dairy producer is a good example of successful implementation of research results in the product development of an enterprise.

“What I particularly appreciate in the cooperation with Tere is its longevity: the enterprise has managed to keep ME-3 in their products attractive for the consumers, despite the fierce competition in the food industry. ME-3 is clearly a very efficient probiotic,” said Puura, satisfied with the continuation of the cooperation.

Tere’s Marketing Director Alar Pink added that using the bacteria discovered at the university has taken the product group of Hellus kefir, traditional fermented milk drink, among the bestselling in Estonia.

The yogurt, fermented milk and kefir products of the Hellus product line contain the probiotic bacteria Lactobacillus fermentum ME-3 discovered at the UT. This is a patented invention “Lactobacillus fermentum ME-3 – an antimicrobial and antioxidative probiotic” by the UT researchers Marika Mikelsaar, Mihkel Zilmer, Tiiu Kullisaar, Heidi Annuk and Epp Songisepp.

In 2013, Marika Mikelsaar was nominated for the World Food Prize for the discovery.

Lactobacillus fermentum ME-3 is unique as it combines two aspects: it is antimicrobial and antioxidative at the same time. Thus it has a direct destructive effect on microbes and a beneficial effect on the human organism.

In 2014, in cooperation with the French development partner VF Bioscience, the ME-3 also reached the cholesterol-reducing food supplement Reg’Activ Cholesterol. The supplement is already sold in pharmacies in Estonia, France, the Philippines and, since March 2015, also in the US.

Read this article again @ http://news.err.ee/v/scitech/2f232288-f577-4b4c-8209-d01df21585e1

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Could story-based video games help people with autism?

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Could story-based video games help people with autism?

New research into nonviolent video games suggests that games promoting storytelling over action may have prosocial benefits for people with autism.

Previous research has suggested that when games satisfy the social needs of the player, motivation to continue playing is boosted and the players report a more immersive experience and enhanced well-being.

“The motivation to engage in and enjoy video games corresponds with principals that apply to human motivation in general,” says Daniel Bormann of the University of Freiburg in Germany.

“For instance,” he adds, “successful game franchises offer players a spectrum of meaningful choices to shape the game’s narrative and environment, provide carefully balanced challenges, or encourage players to experience social connectedness and meaningful social interactions.”

For their new study, published in the journal Social and Personality Psychology Science, Bormann and colleagues wanted to investigate whether this immersion is fostered by storytelling and whether it affects players’ ability to assess the mental states of other people.

To do this, the authors randomly assigned participants to play one of two games – “Gone Home” or “Against the Wall.”

In “Against the Wall,” the players were required to scale an infinite wall in a surreal landscape. “Gone Home,” meanwhile, is a story-based game where the player adopts the role of a female American college student who has returned from a year abroad to find her family missing and their home empty.

Following a 20-minute play period, all participants took part in a task requiring them to assess the emotions behind facial expressions and completed a survey on the extent to which they experienced immersion and need-satisfaction while playing the game.

How did the games affect immersion and social abilities?

Bormann defines immersion as “an experience you might have enjoyed while watching your favorite movie for the first time – the sensation of being transported to another time or space, as though you are taking a real journey, or the feeling of being emotionally impacted by the protagonist’s fate.”

The study shows that the players of the story-based game were more immersed than the players of “Against the Wall.” The feedback from the “Gone Home” players also suggested that being immersed in the game’s story supported the players in “perceiving opportunities for meaningful choices and relationships.”

Interestingly, the narrative elements of the story-based game were also found to improve, in certain situations, the players’ “theory of mind” – their ability to accurately assess the mental states of others. Bormann explains:

“Although the effects regarding theory of mind were relatively small, we were excited to see initial evidence for the short-term enhancement through in-game storytelling. Importantly, this effect was specific to the condition in which participants actively engaged in the games narration, while the mere exposure to the narrative video game did not affect theory of mind, in comparison to playing a neutral video game.”

Clinicians and software developers could use this knowledge to develop treatment aids for people with social-interaction impairments, such as autism spectrum disorders, Bormann concludes. However, the authors acknowledge that more work needs to be done to examine the effects game-based storytelling might have on real-life social interaction.

Written by David McNamee

source: http://www.medicalnewstoday.com/articles/292241.php

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Inkjet Printing of Flexible Electronics for Body-Worn Medical Devices

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Inkjet Printing of Flexible Electronics for Body-Worn Medical Devices

Flexible electronics have the potential to revolutionize medicine, and they’ve already shown a lot of promise though the technology is still in an early development. In order to bring it to the next stage, easy and cheap methods for printing flexible electronic circuits are a necessity. Researchers at Purdue University have developed a new inkjet printing technique that can print elastic and stretchable wires onto different kinds of materials at a low cost and at high speed.

The team used nanoparticles of gallium-indium that were dispersed through a liquid solvent using ultrasound. The solution can be run through an inkjet printer, the metal particles being small enough to pass through the nozzles. Once the solvent dries, the metal nanoparticles stay on the surface they were printed on, creating a conducting wire that will stretch and flex along with the material its attached to.

From the study abstract in Advanced Materials:

Liquid metal nanoparticles that are mechanically sintered at and below room temperature are introduced. This material can be sintered globally on large areas of entire deposits or locally to create liquid traces within deposits. The metallic nanoparticles are fabricated by dispersing a liquid metal in a carrier solvent via sonication. The resulting dispersion is compatible with inkjet printing, a process not applicable to the bulk liquid metal in air.

Study in Advanced Materials: Mechanically Sintered Gallium–Indium Nanoparticles…

Source: Purdue…

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Brilliant spark for personalised therapies

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Brilliant spark for personalised therapies

The 2015 Spark Award goes to a group of researchers led by ETH Professor Manfred Kopf, which has developed a method by which specific characteristics of immune cells can be identified. The technology could prove to be an important tool in personalised medicine.

A total of 145 inventions, 82 of which have been registered for patent approval: ETH Zurich researchers developed many brilliant ideas for new technologies in 2014. Every year, ETH nominates the technologies with the greatest commercial potential for the Spark Award. External judges and specialists from ETH transfer, ETH Zurich’s technology transfer unit, evaluate the inventions. Apart from the commercial potential also originality and  patent strength are taken into account..

“Have you ever wondered what a spark is?” asked Detlef Günther, Vice President Research and Corporate Relations of ETH Zürich in his welcome speech at this year’s Spark Award ceremony. A spark is something that is really highly energetic, explained Günther, a charged particle that emits light. And that energy transfer typically starts from one single particle or from a group, and typically the strongest one. “Today we hope to find the most innovative particle or group of particles with the most innovative idea in this room.”

This year, ETH Professor Manfred Kopf and his colleagues Jan Kisielow and Franz-Josef Obermair receive the Spark Award for a new technology that allows large scale and simple characterisation of specific immune cells, called T-cells. “We hope our technology will be an important tool in many clinical areas, be it diagnostics or individualised therapies,” says Kisielow, a research associate at the Institute for Molecular Health Sciences.

Target search in high-throughput

T-cells carry specific receptors that recognise virus-infected or degenerate cells in the body so that they can render them harmless. When T-cells mature, countless variants with different receptors develop that recognise each other’s target structures (antigens). A complex immune selection process eliminates those T-cells that recognise the body’s healthy cells. Remaining is a battalion of T-cells with different receptors that match all kinds of extraneous and abnormal antigens. In autoimmune diseases, such as polyarthritis or multiple sclerosis, T-cells develop with receptors that incorrectly identify and attack healthy cells in the body.


Jan Kisielow explains in a video how their technology allows to characterise specific characterstics of T cells.

The technology developed by Kopf, Kisielow and Obermair is a high-throughput method by which the antigens recognised by T-cells can be identified. A cell equipped with a light signal presents an antigen from a library of candidate molecules on its surface. If a T-cell with its receptor now binds to the presented molecule, the light signal is switched on and contact between the T-cell and the antigen is immediately reported. Through the light signal, the antigen can be picked out from the library and identified.

This invention could enable the development of customised therapies for patients. For example, if one knows the target peptide of the stray T-cells in an autoimmune disease, it may be possible to mask it in order to protect the healthy cells. It is also conceivable that the degenerate T-cells in the patient’s blood could be used as an indicator in the diagnosis of autoimmune diseases. In addition, T-cells found in close proximity to a tumour could provide insight into new tumour antigens, which may allow customised cancer immunotherapy.

For further dialogues with the scientists read more at: https://www.ethz.ch/en/news-and-events/eth-news/news/2015/04/brilliant-spark-for-personalised-therapies.html

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Even doctors rely on Dr. Google

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Even doctors rely on Dr. Google

In Italy, it’s not just members of the public who rely on the Internet to search for information about their health. Now the vast majority of doctors (nine out of 10) also ‘study’ online. This is a finding that came to light in GFK-Eurisko’s 2014 research on Digital Doctor Communication, which highlighted a real paradox: the more time doctors spend on the Internet updating their knowledge, the more quality time they can devote to patients.

The truth is that medical-scientific information is now primarily available on the web, so medical staff are simply adapting to this. About 80% of doctors now have remote or tele-detailing; 30% are already receiving scientific updates online; 70% own a smartphone, compared to 50% in 2013, while 50% have a tablet.

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Bras that treat breast cancer

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Bras that treat breast cancer

A British student, Sarah Da Costa, has created the Foxleaf Bra, a bra that releases anti-cancer drugs directly into the body.

The revolutionary garment contains tamoxifen in tiny micro-capsules in soft inserts inside the bra. Body heat and sweat, as well as continuous friction between the skin and fabric, rupture the particles and release the right amount of medicine, which is gradually absorbed by the skin throughout the day. It’s a simple and effective treatment that could potentially reduce the drug’s unpleasant side effects such as hot flashes, nausea and stomach cramps. Applying the drug locally also prevents strain on the liver, a problem with oral therapies. Da Costa’s next project is to see if a similar technology could be used to deliver dementia drugs via bed sheets or through clothing.

As it is written on the site of Materialfutures.com, where the idea is presented :

Can we engineer therapeutic properties to soft surfaces for disease prevention?

Exploring the current bio-technology of ‘microencapsulation’, or rather, the embedding of a drug within a textile, I am interested in how soft surfaces could be used as an alternative to existing, conventional modes of drug delivery for disease prevention.

Working closely with Dr. Ipsita Roy, UK Reader of Microbial Biotechnology at the University of Westminster, I have developed a bra for young women prone to developing breast cancer that has the drug Tamoxifen micro-encapsulated within it.

By developing a bio-polymer and embedding it within a bra, it is now possible to deliver the effective drug Tamoxifen through skin contact, which not only enables us to deliver the treatment at the core site, but also help young women avoid the traumatic side effects of the drug when taken orally.

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Neulasta On-body Injector Makes Sure Drug Administered Following Chemo

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Neulasta On-body Injector Makes Sure Drug Administered Following Chemo

Neulasta (pegfilgrastim) is administered to patients the day after chemotherapy to boost the production of white blood cells that help fight infection. Now a new product from Amgen, the manufacturer of Neulasta, will allow clinicians to stick a patch to a patient’s skin right after chemo that will deliver the full dose of the medication a day later.

This will guarantee that the patients receive the Neulasta while letting them rest comfortably at home after therapy. Additionally, one less visit per patient will free up a lot of valuable time at the clinic.

Some details from Amgen:

In addition to the On-body Injector, the Neulasta Delivery Kit includes a specifically designed Neulasta prefilled syringe along with HCP and Patient Instructions for Use and a Quick Reference Guide. On the same day as a chemotherapy session, the HCP initiates Neulasta administration by using the co-packaged syringe to fill the injector and activate it. The On-body Injector is then applied to the patient, to deliver Neulasta approximately 27 hours after the administration of cytotoxic chemotherapy. Activation of the injector leads to the subsequent insertion of the subcutaneous cannula while under HCP supervision. The HCP then reviews and  provides the patient with the Patient Instructions for Use, which includes information about the On-body Injector for Neulasta and what the patient can expect while wearing it.   

source: http://www.medgadget.com/2015/03/neulasta-on-body-injector-makes-sure-drug-administered-following-chemo.html

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